7RUX

Crystal structure of the BCL6 BTB domain in complex with OICR-8311

Summary for 7RUX

• Entry DOI: 10.2210/pdb7rux/pdb
• Related: 7LWE 7LWF 7LWG
• Descriptor: B-cell lymphoma 6 protein, N-(3-chloropyridin-4-yl)-2-(3-(cyclopropylmethyl)-4-oxo-3,4-dihydro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)acetamide, FORMIC ACID, ... (4 entities in total)
• Functional Keywords: immunity, inflammatory response, transcription repressor, transcription-transcription inhibitor complex, transcription/transcription inhibitor
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 15070.71

Authors

Kuntz, D.A.,Prive, G.G. (deposition date: 2021-08-18, release date: 2022-11-09, Last modification date: 2023-10-18)

• Primary citation: Watson, I.,Isaac, M.; Crystal structure of the BCL6 BTB domain in complex with OICR-8311; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.3 Å)