7RU3

CC6.33 IgG in complex with SARS-CoV-2-6P-Mut7 S protein (non-uniform refinement)

7RU3 の概要

• エントリーDOI: 10.2210/pdb7ru3/pdb
• EMDBエントリー: 24695
• 分子名称: CC6.33 IgG heavy chain Fv, CC6.33 IgG Kappa chain Fv, Spike glycoprotein, ... (6 entities in total)
• 機能のキーワード: covid, sars-cov-2, stabilizing mutations, neutralizing antibody, rbd, viral protein, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Homo sapiens; 詳細
• タンパク質・核酸の鎖数: 7
• 化学式量合計: 482021.43

構造登録者

Ozorowski, G.,Turner, H.L.,Ward, A.B. (登録日: 2021-08-16, 公開日: 2022-08-24, 最終更新日: 2022-09-14)

• 主引用文献: Zhao, F.,Keating, C.,Ozorowski, G.,Shaabani, N.,Francino-Urdaniz, I.M.,Barman, S.,Limbo, O.,Burns, A.,Zhou, P.,Ricciardi, M.J.,Woehl, J.,Tran, Q.,Turner, H.L.,Peng, L.,Huang, D.,Nemazee, D.,Andrabi, R.,Sok, D.,Teijaro, J.R.,Whitehead, T.A.,Ward, A.B.,Burton, D.R.,Jardine, J.G.; Engineering SARS-CoV-2 neutralizing antibodies for increased potency and reduced viral escape pathways.; Iscience, 25:104914-104914, 2022; PubMed: 35971553; DOI: 10.1016/j.isci.2022.104914

実験手法

ELECTRON MICROSCOPY (3.3 Å)