7RRF

Carbonic Anhydrase IX-mimic in complex with Beta-Galactose_2C

7RRF の概要

• エントリーDOI: 10.2210/pdb7rrf/pdb
• 分子名称: Carbonic anhydrase 2, 2-[1-(1,1,3-trioxo-2,3-dihydro-1H-1lambda~6~,2-benzothiazol-6-yl)-1H-1,2,3-triazol-4-yl]ethyl beta-L-gulopyranoside, ZINC ION, ... (4 entities in total)
• 機能のキーワード: cancer, galactose, inhibitor, metal binding protein, ligase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 29888.14

構造登録者

Combs, J.E.,McKenna, R. (登録日: 2021-08-09, 公開日: 2022-08-24, 最終更新日: 2023-10-18)

• 主引用文献: Combs, J.E.,Murray, A.B.,Lomelino, C.L.,Mboge, M.Y.,Frost, S.C.,Horenstein, N.A.,McKenna, R.,Becker, H.M.; Inhibition of Carbonic Anhydrase IX and Monocarboxylate Transporters 1 and 4 in breast cancer via novel inhibition with Beta-Galactose 2C; To Be Published,

実験手法

X-RAY DIFFRACTION (1.45 Å)