7RGX
Crystal structure of human galectin-3 CRD in complex with Methyl 2-O-(2-nitrobenzoyl)-3-O-(4-methylbenzoyl)-b-D-talopyranoside
Summary for 7RGX
Entry DOI | 10.2210/pdb7rgx/pdb |
Descriptor | Galectin-3, CHLORIDE ION, methyl 3-O-(4-methylbenzoyl)-2-O-(2-nitrobenzoyl)-beta-D-talopyranoside, ... (4 entities in total) |
Functional Keywords | carbohydrate-binding protein, sugar binding protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 16232.00 |
Authors | Bum-Erdene, K.,Kishor, C.,Blanchard, H. (deposition date: 2021-07-15, release date: 2022-07-13, Last modification date: 2023-10-18) |
Primary citation | Bum-Erdene, K.,Collins, P.M.,Hugo, M.W.,Tarighat, S.S.,Fei, F.,Kishor, C.,Leffler, H.,Nilsson, U.J.,Groffen, J.,Grice, I.D.,Heisterkamp, N.,Blanchard, H. Novel Selective Galectin-3 Antagonists Are Cytotoxic to Acute Lymphoblastic Leukemia. J.Med.Chem., 65:5975-5989, 2022 Cited by PubMed: 35427125DOI: 10.1021/acs.jmedchem.1c01296 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.58 Å) |
Structure validation
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