7RG8

Crystal Structure of a Stable Heparanase Mutant

Summary for 7RG8

• Entry DOI: 10.2210/pdb7rg8/pdb
• Descriptor: Heparanase 50 kDa subunit, Heparanase 8 kDa subunit, ACETATE ION, ... (5 entities in total)
• Functional Keywords: heparanase, heparan sulfate, hydrolase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 53794.41

Authors

Whitefield, C.,Hong, N.S.,Jackson, C.J. (deposition date: 2021-07-14, release date: 2022-03-02, Last modification date: 2023-10-18)

• Primary citation: Whitefield, C.,Hong, N.,Mitchell, J.A.,Jackson, C.J.; Computational design and experimental characterisation of a stable human heparanase variant.; Rsc Chem Biol, 3:341-349, 2022; PubMed: 35382258; DOI: 10.1039/d1cb00239b

Experimental method

X-RAY DIFFRACTION (1.3 Å)