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7RCC

First stage engineered variant of I-OnuI after initial reassembly

Summary for 7RCC
Entry DOI10.2210/pdb7rcc/pdb
DescriptorI-OnuI_e-hPD1-b, DNA (26-MER), CALCIUM ION, ... (5 entities in total)
Functional Keywordsmeganuclease, gene editing, protein engineering, dna binding protein-dna complex, dna binding protein/dna
Biological sourceSynthetic construct
More
Total number of polymer chains9
Total formula weight153406.78
Authors
Ubilla-Rodriguez, N.C.,Werther, R.A.,Stoddard, B.L. (deposition date: 2021-07-07, release date: 2022-06-29, Last modification date: 2023-10-18)
Primary citationWerther, R.A.,Ubilla-Rodriguez, N.C.,Smiley, A.T.,Havens, K.,Lambert, A.R.,Stoddard, B.L.
Characterization of the stepwise engineering and optimization of a retargeted DNA binding protein and gene-editing meganuclease
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.45 Å)
Structure validation

221051

數據於2024-06-12公開中

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