7RC6
Aeronamide N-methyltransferase, AerE, bound to modified peptide substrate, AerA-DL,34
Summary for 7RC6
Entry DOI | 10.2210/pdb7rc6/pdb |
Descriptor | Methyltransferase family protein, Aeronamide A peptide, SODIUM ION, ... (5 entities in total) |
Functional Keywords | sam-dependent, peptide cytotoxin, proteusin, biosynthetic protein, transferase-biosynthetic protein complex, transferase/biosynthetic protein |
Biological source | Microvirgula aerodenitrificans DSM 15089 More |
Total number of polymer chains | 2 |
Total formula weight | 45473.30 |
Authors | Cogan, D.P.,Reyes, R.,Nair, S.K. (deposition date: 2021-07-07, release date: 2022-03-30, Last modification date: 2023-11-15) |
Primary citation | Cogan, D.P.,Bhushan, A.,Reyes, R.,Zhu, L.,Piel, J.,Nair, S.K. Structure and mechanism for iterative amide N -methylation in the biosynthesis of channel-forming peptide cytotoxins. Proc.Natl.Acad.Sci.USA, 119:e2116578119-e2116578119, 2022 Cited by PubMed: 35316135DOI: 10.1073/pnas.2116578119 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.71 Å) |
Structure validation
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