7RC6

Aeronamide N-methyltransferase, AerE, bound to modified peptide substrate, AerA-DL,34

Summary for 7RC6

Entry DOI	10.2210/pdb7rc6/pdb
Descriptor	Methyltransferase family protein, Aeronamide A peptide, SODIUM ION, ... (5 entities in total)
Functional Keywords	sam-dependent, peptide cytotoxin, proteusin, biosynthetic protein, transferase-biosynthetic protein complex, transferase/biosynthetic protein
Biological source	Microvirgula aerodenitrificans DSM 15089 More
Total number of polymer chains	2
Total formula weight	45473.30
Authors	Cogan, D.P.,Reyes, R.,Nair, S.K. (deposition date: 2021-07-07, release date: 2022-03-30, Last modification date: 2023-11-15)
Primary citation	Cogan, D.P.,Bhushan, A.,Reyes, R.,Zhu, L.,Piel, J.,Nair, S.K. Structure and mechanism for iterative amide N -methylation in the biosynthesis of channel-forming peptide cytotoxins. Proc.Natl.Acad.Sci.USA, 119:e2116578119-e2116578119, 2022 Cited by PubMed: 35316135 DOI: 10.1073/pnas.2116578119 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.71 Å)

Structure validation