7RC6

Aeronamide N-methyltransferase, AerE, bound to modified peptide substrate, AerA-DL,34

7RC6 の概要

• エントリーDOI: 10.2210/pdb7rc6/pdb
• 分子名称: Methyltransferase family protein, Aeronamide A peptide, SODIUM ION, ... (5 entities in total)
• 機能のキーワード: sam-dependent, peptide cytotoxin, proteusin, biosynthetic protein, transferase-biosynthetic protein complex, transferase/biosynthetic protein
• 由来する生物種: Microvirgula aerodenitrificans DSM 15089; 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 45473.30

構造登録者

Cogan, D.P.,Reyes, R.,Nair, S.K. (登録日: 2021-07-07, 公開日: 2022-03-30, 最終更新日: 2023-11-15)

• 主引用文献: Cogan, D.P.,Bhushan, A.,Reyes, R.,Zhu, L.,Piel, J.,Nair, S.K.; Structure and mechanism for iterative amide N -methylation in the biosynthesis of channel-forming peptide cytotoxins.; Proc.Natl.Acad.Sci.USA, 119:e2116578119-e2116578119, 2022; PubMed: 35316135; DOI: 10.1073/pnas.2116578119

実験手法

X-RAY DIFFRACTION (1.71 Å)