7RBY

Crystal structure of Nanobody nb112 and SARS-CoV-2 RBD

7RBY の概要

• エントリーDOI: 10.2210/pdb7rby/pdb
• 分子名称: Spike protein S1, Ilama-isolated nanobody NIH-CoV nb-112 specific to SARS-CoV-2 RBD, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: sars-cov-2, nanobody, rbd-specific, broad neutralization, viral protein
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2; 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 75756.73

構造登録者

Chen, Y.,Tolbert, W.,Pazgier, M. (登録日: 2021-07-06, 公開日: 2022-03-23, 最終更新日: 2023-10-18)

• 主引用文献: Esparza, T.J.,Chen, Y.,Martin, N.P.,Bielefeldt-Ohmann, H.,Bowen, R.A.,Tolbert, W.D.,Pazgier, M.,Brody, D.L.; Nebulized delivery of a broadly neutralizing SARS-CoV-2 RBD-specific nanobody prevents clinical, virological, and pathological disease in a Syrian hamster model of COVID-19.; Mabs, 14:2047144-2047144, ; PubMed: 35289719; DOI: 10.1080/19420862.2022.2047144

実験手法

X-RAY DIFFRACTION (2.82 Å)