7RB6

Low temperature structure of hAChE in complex with substrate analog 4K-TMA

7RB6 の概要

• エントリーDOI: 10.2210/pdb7rb6/pdb
• 分子名称: Acetylcholinesterase, 4,4-DIHYDROXY-N,N,N-TRIMETHYLPENTAN-1-AMINIUM, GLYCEROL, ... (5 entities in total)
• 機能のキーワード: acetylcholine esterase, serine hydrolase, tetrahedral intermediate, hydrolase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 121484.93

構造登録者

Kovalevsky, A.,Gerlits, O.,Radic, Z. (登録日: 2021-07-05, 公開日: 2021-09-22, 最終更新日: 2023-10-18)

• 主引用文献: Gerlits, O.,Blakeley, M.P.,Keen, D.A.,Radic, Z.,Kovalevsky, A.; Room temperature crystallography of human acetylcholinesterase bound to a substrate analogue 4K-TMA: Towards a neutron structure; Curr Res Struct Biol, 3:206-215, 2021; DOI: 10.1016/j.crstbi.2021.08.003

実験手法

X-RAY DIFFRACTION (2.4 Å)