7RAL

SARS-CoV-2 S bound to S2X259 Fab (local refinement of the RBD/S2X259 variable domains)

7RAL の概要

• エントリーDOI: 10.2210/pdb7ral/pdb
• EMDBエントリー: 24365
• 分子名称: S2X259 Fab heavy chain, S2X259 Fab light chain, Spike glycoprotein, ... (4 entities in total)
• 機能のキーワード: sars-cov-2, spike glycoprotein, fab s2x259, viral protein, structural genomics, seattle structural genomics center for infectious disease, ssgcid, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Homo sapiens; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 168110.86

構造登録者

Veesler, D.,Tortorici, M.A.,Seattle Structural Genomics Center for Infectious Disease (SSGCID) (登録日: 2021-07-01, 公開日: 2021-08-04, 最終更新日: 2021-09-15)

• 主引用文献: Tortorici, M.A.,Czudnochowski, N.,Starr, T.N.,Marzi, R.,Walls, A.C.,Zatta, F.,Bowen, J.E.,Jaconi, S.,Di Iulio, J.,Wang, Z.,De Marco, A.,Zepeda, S.K.,Pinto, D.,Liu, Z.,Beltramello, M.,Bartha, I.,Housley, M.P.,Lempp, F.A.,Rosen, L.E.,Dellota Jr., E.,Kaiser, H.,Montiel-Ruiz, M.,Zhou, J.,Addetia, A.,Guarino, B.,Culap, K.,Sprugasci, N.,Saliba, C.,Vetti, E.,Giacchetto-Sasselli, I.,Fregni, C.S.,Abdelnabi, R.,Foo, S.C.,Havenar-Daughton, C.,Schmid, M.A.,Benigni, F.,Cameroni, E.,Neyts, J.,Telenti, A.,Virgin, H.W.,Whelan, S.P.J.,Snell, G.,Bloom, J.D.,Corti, D.,Veesler, D.,Pizzuto, M.S.; Broad sarbecovirus neutralization by a human monoclonal antibody.; Nature, 597:103-108, 2021; PubMed: 34280951; DOI: 10.1038/s41586-021-03817-4

実験手法

ELECTRON MICROSCOPY