7R91

cryo-EM structure of the rigor state wild type myosin-15-F-actin complex

Summary for 7R91

• Entry DOI: 10.2210/pdb7r91/pdb
• EMDB information: 24321 24322
• Descriptor: Actin, alpha skeletal muscle, intermediate form, Isoform 3 of Unconventional myosin-XV, ADENOSINE-5'-DIPHOSPHATE, ... (4 entities in total)
• Functional Keywords: myosin motor proteins, actin cytoskeleton, stereocilia, deafness, motor protein
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 4
• Total formula weight: 204431.51

Authors

Gong, R.,Reynolds, M.J.,Gurel, P.,Alushin, G.M. (deposition date: 2021-06-28, release date: 2021-07-28, Last modification date: 2022-08-03)

• Primary citation: Gong, R.,Jiang, F.,Moreland, Z.G.,Reynolds, M.J.,de Los Reyes, S.E.,Gurel, P.,Shams, A.,Heidings, J.B.,Bowl, M.R.,Bird, J.E.,Alushin, G.M.; Structural basis for tunable control of actin dynamics by myosin-15 in mechanosensory stereocilia.; Sci Adv, 8:eabl4733-eabl4733, 2022; PubMed: 35857845; DOI: 10.1126/sciadv.abl4733

Experimental method

ELECTRON MICROSCOPY (2.83 Å)