7R40

Structure of the SARS-CoV-2 spike glycoprotein in complex with the 87G7 antibody Fab fragment

7R40 の概要

• エントリーDOI: 10.2210/pdb7r40/pdb
• EMDBエントリー: 14250
• 分子名称: Spike glycoprotein, 87G7 light chain variable region, 87G7 heavy chain variable region, ... (5 entities in total)
• 機能のキーワード: coronavirus, spike, antibody, complex, viral protein
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2; 詳細
• タンパク質・核酸の鎖数: 9
• 化学式量合計: 576609.36

構造登録者

Hurdiss, D.L. (登録日: 2022-02-08, 公開日: 2022-04-20, 最終更新日: 2023-12-13)

• 主引用文献: Du, W.,Hurdiss, D.L.,Drabek, D.,Mykytyn, A.Z.,Kaiser, F.K.,Gonzalez-Hernandez, M.,Munoz-Santos, D.,Lamers, M.M.,van Haperen, R.,Li, W.,Drulyte, I.,Wang, C.,Sola, I.,Armando, F.,Beythien, G.,Ciurkiewicz, M.,Baumgartner, W.,Guilfoyle, K.,Smits, T.,van der Lee, J.,van Kuppeveld, F.J.M.,van Amerongen, G.,Haagmans, B.L.,Enjuanes, L.,Osterhaus, A.D.M.E.,Grosveld, F.,Bosch, B.J.; An ACE2-blocking antibody confers broad neutralization and protection against Omicron and other SARS-CoV-2 variants of concern.; Sci Immunol, 7:eabp9312-eabp9312, 2022; PubMed: 35471062; DOI: 10.1126/sciimmunol.abp9312

実験手法

ELECTRON MICROSCOPY (2.9 Å)