7R1Q

X-ray structure of the adduct formed upon reaction of the gold(I) N-heterocyclic carbene complex Au2 with lysozyme

This is a non-PDB format compatible entry.

Summary for 7R1Q

• Entry DOI: 10.2210/pdb7r1q/pdb
• Descriptor: Lysozyme, DIMETHYL SULFOXIDE, GOLD ION, ... (4 entities in total)
• Functional Keywords: metallodrug, protein-metal interaction, gold, carbene, anticancer, hydrolase
• Biological source: Gallus gallus (chicken)
• Total number of polymer chains: 1
• Total formula weight: 15000.19

Authors

Merlino, A.,Ferraro, G. (deposition date: 2022-02-03, release date: 2022-07-13, Last modification date: 2024-01-31)

• Primary citation: Annunziata, A.,Ferraro, G.,Cucciolito, M.E.,Imbimbo, P.,Tuzi, A.,Monti, D.M.,Merlino, A.,Ruffo, F.; Halo complexes of gold(I) containing glycoconjugate carbene ligands: synthesis, characterization, cytotoxicity and interaction with proteins and DNA model systems.; Dalton Trans, 51:10475-10485, 2022; PubMed: 35766118; DOI: 10.1039/d2dt00423b

Experimental method

X-RAY DIFFRACTION (1.1 Å)