7QZ9
Transcriptional regulator LmrR with Trp-67 and Trp-96 replaced by the unnatural amino acid 5,6-difluoroTrp
Summary for 7QZ9
| Entry DOI | 10.2210/pdb7qz9/pdb |
| Related | 7QZ5 7QZ6 7QZ7 7QZ8 |
| Descriptor | Transcriptional regulator, PadR-like family (1 entity in total) |
| Functional Keywords | transcriptional regulator, padr, fluorinated tryptophan, daunomycin, pi-pi interactions, dna binding protein |
| Biological source | Lactococcus cremoris |
| Total number of polymer chains | 2 |
| Total formula weight | 28758.43 |
| Authors | Thunnissen, A.M.W.H. (deposition date: 2022-01-30, release date: 2022-11-23, Last modification date: 2024-01-31) |
| Primary citation | Shao, J.,Kuiper, B.P.,Thunnissen, A.W.H.,Cool, R.H.,Zhou, L.,Huang, C.,Dijkstra, B.W.,Broos, J. The Role of Tryptophan in pi Interactions in Proteins: An Experimental Approach. J.Am.Chem.Soc., 144:13815-13822, 2022 Cited by PubMed: 35868012DOI: 10.1021/jacs.2c04986 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.31 Å) |
Structure validation
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