7QZ6

Transcriptional regulator LmrR with bound daunomycin and with Trp-67 and Trp-96 replaced by 5-fluoroTrp

Summary for 7QZ6

Entry DOI	10.2210/pdb7qz6/pdb
Related	7QZ5 7QZ7 7QZ8 7QZ9
Descriptor	Transcriptional regulator, PadR-like family, DAUNOMYCIN (3 entities in total)
Functional Keywords	transcriptional regulator, padr, fluorinated tryptophan, daunomycin, pi-pi interactions, dna binding protein
Biological source	Lactococcus cremoris
Total number of polymer chains	2
Total formula weight	29213.99
Authors	Thunnissen, A.M.W.H. (deposition date: 2022-01-30, release date: 2022-11-23, Last modification date: 2024-01-31)
Primary citation	Shao, J.,Kuiper, B.P.,Thunnissen, A.W.H.,Cool, R.H.,Zhou, L.,Huang, C.,Dijkstra, B.W.,Broos, J. The Role of Tryptophan in pi Interactions in Proteins: An Experimental Approach. J.Am.Chem.Soc., 144:13815-13822, 2022 Cited by PubMed: 35868012 DOI: 10.1021/jacs.2c04986 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.15 Å)

Structure validation