7QYT
BAZ2A bromodomain in complex with acetylpyrrole derivative compound 80
Summary for 7QYT
| Entry DOI | 10.2210/pdb7qyt/pdb |
| Related | 7QXL 7QYE 7QYO |
| Descriptor | Bromodomain adjacent to zinc finger domain protein 2A, 3-methyl-1-(2-piperazin-1-yl-1,3-thiazol-4-yl)-2,5,6,7-tetrahydroisoindol-4-one (3 entities in total) |
| Functional Keywords | four helical bundle, transcription |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 12996.71 |
| Authors | Dalle Vedove, A.,Cazzanelli, G.,Caflisch, A.,Lolli, G. (deposition date: 2022-01-29, release date: 2022-09-28, Last modification date: 2024-01-31) |
| Primary citation | Dalle Vedove, A.,Cazzanelli, G.,Batiste, L.,Marchand, J.R.,Spiliotopoulos, D.,Corsi, J.,D'Agostino, V.G.,Caflisch, A.,Lolli, G. Identification of a BAZ2A-Bromodomain Hit Compound by Fragment Growing. Acs Med.Chem.Lett., 13:1434-1443, 2022 Cited by PubMed: 36105334DOI: 10.1021/acsmedchemlett.2c00173 PDB entries with the same primary citation |
| Experimental method |
Structure validation
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