7QVO

Crystal structure of the C-terminal catalytic domain of Plasmodium falciparum CTP:phosphocholine cytidylyltransferase with guanidine

7QVO の概要

• エントリーDOI: 10.2210/pdb7qvo/pdb
• 分子名称: Cholinephosphate cytidylyltransferase, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Guanidinium, ... (4 entities in total)
• 機能のキーワード: plasmodium falciparum cct inhibitors fragments, transferase
• 由来する生物種: Plasmodium falciparum (malaria parasite P. falciparum)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 21052.42

構造登録者

Duclovel, C.,Gelin, M.,Krimm, I.,Cerdan, R.,Guichou, J.-F. (登録日: 2022-01-22, 公開日: 2023-01-25, 最終更新日: 2024-02-07)

• 主引用文献: Duclovel, C.,Gelin, M.,Wein, S.,Wengelnik, K.,Krimm, I.,Guichou, J.F.,Cerdan, R.; Crystallographic screening using ultra-low-molecular-weight ligands to guide drug design of PfCCT inhibitors; To Be Published,

実験手法

X-RAY DIFFRACTION (1.62 Å)