7QTZ
Crystal structure of Iripin-1 serpin from tick Ixodes ricinus
Summary for 7QTZ
| Entry DOI | 10.2210/pdb7qtz/pdb |
| Descriptor | Putative salivary serpin, MAGNESIUM ION (3 entities in total) |
| Functional Keywords | ixodes ricinus, iripin-1, crystal, hydrolase, immunosuppressant |
| Biological source | Ixodes ricinus (castor bean tick) |
| Total number of polymer chains | 2 |
| Total formula weight | 84681.47 |
| Authors | Kascakova, B.,Kuta Smatanova, I.,Chmelar, J.,Prudnikova, T. (deposition date: 2022-01-17, release date: 2023-01-25, Last modification date: 2024-02-07) |
| Primary citation | Chlastakova, A.,Kascakova, B.,Kotal, J.,Langhansova, H.,Kotsyfakis, M.,Kuta Smatanova, I.,Tirloni, L.,Chmelar, J. Iripin-1, a new anti-inflammatory tick serpin, inhibits leukocyte recruitment in vivo while altering the levels of chemokines and adhesion molecules. Front Immunol, 14:1116324-1116324, 2023 Cited by PubMed: 36756125DOI: 10.3389/fimmu.2023.1116324 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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