7QT8
Room temperature In-situ SARS-CoV-2 MPRO with bound ABT-957
Summary for 7QT8
Entry DOI | 10.2210/pdb7qt8/pdb |
Descriptor | 3C-like proteinase, (2~{R})-5-oxidanylidene-~{N}-[(2~{R},3~{S})-3-oxidanyl-4-oxidanylidene-1-phenyl-4-(pyridin-2-ylmethylamino)butan-2-yl]-1-(phenylmethyl)pyrrolidine-2-carboxamide (3 entities in total) |
Functional Keywords | protease, dimer, main protease, sars-cov-2, viral protein |
Biological source | Severe acute respiratory syndrome coronavirus 2 |
Total number of polymer chains | 2 |
Total formula weight | 68624.22 |
Authors | Horrell, S.,Gildae, R.J.,Axford, D.,Owen, C.D.,Lukacik, P.,Strain-Damerell, C.,Owen, R.L.,Walsh, M.A. (deposition date: 2022-01-14, release date: 2022-05-04, Last modification date: 2024-01-31) |
Primary citation | Gildea, R.J.,Beilsten-Edmands, J.,Axford, D.,Horrell, S.,Aller, P.,Sandy, J.,Sanchez-Weatherby, J.,Owen, C.D.,Lukacik, P.,Strain-Damerell, C.,Owen, R.L.,Walsh, M.A.,Winter, G. xia2.multiplex: a multi-crystal data-analysis pipeline. Acta Crystallogr D Struct Biol, 78:752-769, 2022 Cited by PubMed: 35647922DOI: 10.1107/S2059798322004399 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.01 Å) |
Structure validation
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