7QT7

Room temperature In-situ SARS-CoV-2 MPRO with bound Z4439011520

7QT7 の概要

• エントリーDOI: 10.2210/pdb7qt7/pdb
• 分子名称: 3C-like proteinase nsp5, N-(5-tert-butyl-1,2-oxazol-3-yl)-N-[(1R)-2-[(4-methoxy-2-methylphenyl)amino]-2-oxo-1-(pyridin-3-yl)ethyl]propanamide, DIMETHYL SULFOXIDE, ... (4 entities in total)
• 機能のキーワード: protease, main protease, sars-cov-2, viral protein
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 34226.08

構造登録者

Horrell, S.,Gildae, R.J.,Axford, D.,Owen, C.D.,Lukacik, P.,Strain-Damerell, C.,Owen, R.L.,Walsh, M.A. (登録日: 2022-01-14, 公開日: 2022-05-04, 最終更新日: 2024-01-31)

• 主引用文献: Gildea, R.J.,Beilsten-Edmands, J.,Axford, D.,Horrell, S.,Aller, P.,Sandy, J.,Sanchez-Weatherby, J.,Owen, C.D.,Lukacik, P.,Strain-Damerell, C.,Owen, R.L.,Walsh, M.A.,Winter, G.; xia2.multiplex: a multi-crystal data-analysis pipeline.; Acta Crystallogr D Struct Biol, 78:752-769, 2022; PubMed: 35647922; DOI: 10.1107/S2059798322004399

実験手法

X-RAY DIFFRACTION (2.25 Å)