7QT4

Antibody FenAb709 - fentanyl complex

Summary for 7QT4

Entry DOI	10.2210/pdb7qt4/pdb
Descriptor	Antibody heavy chain, Antibody light chain, 2-[2-[2-[2-[[5-oxidanylidene-5-[2-[4-[phenyl(propanoyl)amino]piperidin-1-yl]ethylamino]pentanoyl]amino]ethanoylamino]ethanoylamino]ethanoylamino]ethanoic acid, ... (4 entities in total)
Functional Keywords	antibody, immune system
Biological source	Mus musculus More
Total number of polymer chains	2
Total formula weight	48414.70
Authors	Zeelen, J.P.,Straaten van, M.,Stebbins, C.E. (deposition date: 2022-01-14, release date: 2023-05-24, Last modification date: 2024-02-07)
Primary citation	Triller, G.,Vlachou, E.P.,Hashemi, H.,van Straaten, M.,Zeelen, J.P.,Kelemen, Y.,Baehr, C.,Marker, C.L.,Ruf, S.,Svirina, A.,Chandra, M.,Urban, K.,Gkeka, A.,Kruse, S.,Baumann, A.,Miller, A.K.,Bartel, M.,Pravetoni, M.,Stebbins, C.E.,Papavasiliou, F.N.,Verdi, J.P. A trypanosome-derived immunotherapeutics platform elicits potent high-affinity antibodies, negating the effects of the synthetic opioid fentanyl. Cell Rep, 42:112049-112049, 2023 Cited by PubMed: 36719797 DOI: 10.1016/j.celrep.2023.112049 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.32 Å)

Structure validation