7QT0

Antibody FenAb136 - fentanyl complex

Summary for 7QT0

Entry DOI	10.2210/pdb7qt0/pdb
Descriptor	Antibody heavy chain, Antibody light chain, 2-[2-[2-[2-[[5-oxidanylidene-5-[2-[4-[phenyl(propanoyl)amino]piperidin-1-yl]ethylamino]pentanoyl]amino]ethanoylamino]ethanoylamino]ethanoylamino]ethanoic acid, ... (4 entities in total)
Functional Keywords	antibody, immune system
Biological source	Mus musculus More
Total number of polymer chains	12
Total formula weight	291731.89
Authors	Zeelen, J.P.,Straaten van, M.,Stebbins, C.E. (deposition date: 2022-01-14, release date: 2023-05-24, Last modification date: 2024-02-07)
Primary citation	Triller, G.,Vlachou, E.P.,Hashemi, H.,van Straaten, M.,Zeelen, J.P.,Kelemen, Y.,Baehr, C.,Marker, C.L.,Ruf, S.,Svirina, A.,Chandra, M.,Urban, K.,Gkeka, A.,Kruse, S.,Baumann, A.,Miller, A.K.,Bartel, M.,Pravetoni, M.,Stebbins, C.E.,Papavasiliou, F.N.,Verdi, J.P. A trypanosome-derived immunotherapeutics platform elicits potent high-affinity antibodies, negating the effects of the synthetic opioid fentanyl. Cell Rep, 42:112049-112049, 2023 Cited by PubMed: 36719797 DOI: 10.1016/j.celrep.2023.112049 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.07 Å)

Structure validation