7QSR

CryoEM structure of the Ectodomain of Human PLA2R

これはPDB形式変換不可エントリーです。

7QSR の概要

• エントリーDOI: 10.2210/pdb7qsr/pdb
• EMDBエントリー: 14077
• 分子名称: Secretory phospholipase A2 receptor, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: receptor, ectodomain, glycoprotein, nephrology, membrane protein
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 163949.62

構造登録者

Briggs, D.C.,Lockhart-Cairns, M.P.,Baldock, C. (登録日: 2022-01-14, 公開日: 2022-07-20, 最終更新日: 2022-08-03)

• 主引用文献: Fresquet, M.,Lockhart-Cairns, M.P.,Rhoden, S.J.,Jowitt, T.A.,Briggs, D.C.,Baldock, C.,Brenchley, P.E.,Lennon, R.; Structure of PLA2R reveals presentation of the dominant membranous nephropathy epitope and an immunogenic patch.; Proc.Natl.Acad.Sci.USA, 119:e2202209119-e2202209119, 2022; PubMed: 35858348; DOI: 10.1073/pnas.2202209119

実験手法

ELECTRON MICROSCOPY (3.4 Å)