7QIT
CRYSTAL STRUCTURE OF THE P1 trifluoroethylglycine (TfeGly) BPTI MUTANT- BOVINE CHYMOTRYPSIN COMPLEX
Summary for 7QIT
Entry DOI | 10.2210/pdb7qit/pdb |
Related | 7QIQ 7QIR 7QIS |
Descriptor | Chymotrypsin A chain A, Chymotrypsin A chain B, Chymotrypsin A chain C, ... (7 entities in total) |
Functional Keywords | chymotrypsin, serine proteinase, bovine pancreatic trypsin inhibitor, bpti, protein-protein interaction, s1 pocket, primary specificity, hydrolase-hydrolase inhibitor complex, hydrolase |
Biological source | Bos taurus (cattle) More |
Total number of polymer chains | 8 |
Total formula weight | 68284.13 |
Authors | Dimos, N.,Leppkes, J.,Koksch, B.,Wahl, M.C.,Loll, B. (deposition date: 2021-12-15, release date: 2022-03-09, Last modification date: 2024-01-31) |
Primary citation | Leppkes, J.,Dimos, N.,Loll, B.,Hohmann, T.,Dyrks, M.,Wieseke, A.,Keller, B.G.,Koksch, B. Fluorine-induced polarity increases inhibitory activity of BPTI towards chymotrypsin. Rsc Chem Biol, 3:773-782, 2022 Cited by PubMed: 35755190DOI: 10.1039/d2cb00018k PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.99 Å) |
Structure validation
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