7QIQ

CRYSTAL STRUCTURE OF THE P1 aminobutanoic acid (ABU) BPTI MUTANT- BOVINE CHYMOTRYPSIN COMPLEX

Summary for 7QIQ

• Entry DOI: 10.2210/pdb7qiq/pdb
• Related: 7QIR 7QIS 7QIT
• Descriptor: Chymotrypsin A chain A, Chymotrypsin A chain B, Chymotrypsin A chain C, ... (7 entities in total)
• Functional Keywords: chymotrypsin, serine proteinase, bovine pancreatic trypsin inhibitor, bpti, protein-protein interaction, s1 pocket, primary specificity, hydrolase-hydrolase inhibitor complex, hydrolase
• Biological source: Bos taurus (cattle); More
• Total number of polymer chains: 8
• Total formula weight: 67603.78

Authors

Dimos, N.,Leppkes, J.,Koksch, B.,Wahl, M.C.,Loll, B. (deposition date: 2021-12-15, release date: 2022-03-09, Last modification date: 2024-01-31)

• Primary citation: Leppkes, J.,Dimos, N.,Loll, B.,Hohmann, T.,Dyrks, M.,Wieseke, A.,Keller, B.G.,Koksch, B.; Fluorine-induced polarity increases inhibitory activity of BPTI towards chymotrypsin.; Rsc Chem Biol, 3:773-782, 2022; PubMed: 35755190; DOI: 10.1039/d2cb00018k

Experimental method

X-RAY DIFFRACTION (1.85 Å)