7QHH
Desensitized state of GluA1/2 AMPA receptor in complex with TARP-gamma 8 (TMD-LBD)
Summary for 7QHH
Entry DOI | 10.2210/pdb7qhh/pdb |
Related | 7QHB |
EMDB information | 13969 13972 4572 |
Descriptor | Isoform Flip of Glutamate receptor 1, Isoform Flip of Glutamate receptor 2, Voltage-dependent calcium channel gamma-8 subunit, ... (7 entities in total) |
Functional Keywords | glutamate, ampa receptor, tarps, membrane protein |
Biological source | Rattus norvegicus (Norway rat) More |
Total number of polymer chains | 6 |
Total formula weight | 489472.63 |
Authors | Herguedas, B.,Kohegyi, B.,Dohrke, J.N.,Watson, J.F.,Zhang, D.,Ho, H.,Shaikh, S.,Lape, R.,Krieger, J.M.,Greger, I.H. (deposition date: 2021-12-12, release date: 2022-02-23) |
Primary citation | Herguedas, B.,Kohegyi, B.K.,Dohrke, J.N.,Watson, J.F.,Zhang, D.,Ho, H.,Shaikh, S.A.,Lape, R.,Krieger, J.M.,Greger, I.H. Mechanisms underlying TARP modulation of the GluA1/2-gamma 8 AMPA receptor. Nat Commun, 13:734-734, 2022 Cited by PubMed: 35136046DOI: 10.1038/s41467-022-28404-7 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.6 Å) |
Structure validation
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