7QFO
Human Topoisomerase II Beta ATPase AMPPNP
Summary for 7QFO
| Entry DOI | 10.2210/pdb7qfo/pdb |
| Descriptor | DNA topoisomerase 2-beta, ALANINE, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... (5 entities in total) |
| Functional Keywords | dna topoisomerase ii beta, human, atpase domain, top2b, dna binding protein |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 46285.25 |
| Authors | Ling, E.M.,Basle, A.,Cowell, I.G.,Blower, T.R.,Austin, C.A. (deposition date: 2021-12-06, release date: 2022-05-25, Last modification date: 2024-01-31) |
| Primary citation | Ling, E.M.,Basle, A.,Cowell, I.G.,van den Berg, B.,Blower, T.R.,Austin, C.A. A comprehensive structural analysis of the ATPase domain of human DNA topoisomerase II beta bound to AMPPNP, ADP, and the bisdioxopiperazine, ICRF193. Structure, 30:1129-1145.e3, 2022 Cited by PubMed: 35660158DOI: 10.1016/j.str.2022.05.009 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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