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7QD3

Crystal structure of the C-terminal catalytic domain of Plasmodium falciparum CTP:phosphocholine cytidylyltransferase with morpholine

Summary for 7QD3
Entry DOI10.2210/pdb7qd3/pdb
DescriptorCholinephosphate cytidylyltransferase, morpholine (3 entities in total)
Functional Keywordsplasmodium falciparum cct inhibitors fragments, transferase
Biological sourcePlasmodium falciparum
Total number of polymer chains1
Total formula weight20984.36
Authors
Duclovel, C.,Gelin, M.,Krimm, I.,Cerdan, R.,Guichou, J.-F. (deposition date: 2021-11-26, release date: 2022-12-14, Last modification date: 2024-01-31)
Primary citationDuclovel, C.,Gelin, M.,Wein, S.,Wengelnik, K.,Krimm, I.,Guichou, J.F.,Cerdan, R.
Crystallographic screening using ultra-low-molecular-weight ligands to guide drug design of PfCCT inhibitors
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.43 Å)
Structure validation

226707

数据于2024-10-30公开中

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