7QCL

Structure of the MUCIN-2 Cterminal domains

7QCL の概要

• エントリーDOI: 10.2210/pdb7qcl/pdb
• EMDBエントリー: 13896
• 分子名称: Mucin-2, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-[beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]alpha-D-mannopyranose-(1-3)-[beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-[beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
• 機能のキーワード: mucus, extracellular, net assemble, structural protein
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 151331.30

構造登録者

Gallego, P.,Hansson, G.C. (登録日: 2021-11-24, 公開日: 2023-03-08, 最終更新日: 2023-09-27)

• 主引用文献: Gallego, P.,Garcia-Bonete, M.J.,Trillo-Muyo, S.,Recktenwald, C.V.,Johansson, M.E.V.,Hansson, G.C.; The intestinal MUC2 mucin C-terminus is stabilized by an extra disulfide bond in comparison to von Willebrand factor and other gel-forming mucins.; Nat Commun, 14:1969-1969, 2023; PubMed: 37031240; DOI: 10.1038/s41467-023-37666-8

実験手法

ELECTRON MICROSCOPY (3.36 Å)