7QBH
Selenocarbamates as a novel prodrug-based approach towards Carbonic Anhydrase inhibition (hCA II)
This is a non-PDB format compatible entry.
Summary for 7QBH
Entry DOI | 10.2210/pdb7qbh/pdb |
Descriptor | Carbonic anhydrase 2, ZINC ION, phenylmethaneselenol, ... (4 entities in total) |
Functional Keywords | carbonic anhydrase, inhibitor, selenol, selenocarbamate, prodrug, lyase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 29525.57 |
Authors | Angeli, A.,Ferraroni, M. (deposition date: 2021-11-19, release date: 2022-03-16, Last modification date: 2024-01-31) |
Primary citation | Angeli, A.,Ferraroni, M.,Capperucci, A.,Tanini, D.,Costantino, G.,Supuran, C.T. Selenocarbamates As a Prodrug-Based Approach to Carbonic Anhydrase Inhibition. Chemmedchem, 17:e202200085-e202200085, 2022 Cited by PubMed: 35238480DOI: 10.1002/cmdc.202200085 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.223 Å) |
Structure validation
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