7QBH

Selenocarbamates as a novel prodrug-based approach towards Carbonic Anhydrase inhibition (hCA II)

This is a non-PDB format compatible entry.

Summary for 7QBH

• Entry DOI: 10.2210/pdb7qbh/pdb
• Descriptor: Carbonic anhydrase 2, ZINC ION, phenylmethaneselenol, ... (4 entities in total)
• Functional Keywords: carbonic anhydrase, inhibitor, selenol, selenocarbamate, prodrug, lyase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 29525.57

Authors

Angeli, A.,Ferraroni, M. (deposition date: 2021-11-19, release date: 2022-03-16, Last modification date: 2024-01-31)

• Primary citation: Angeli, A.,Ferraroni, M.,Capperucci, A.,Tanini, D.,Costantino, G.,Supuran, C.T.; Selenocarbamates As a Prodrug-Based Approach to Carbonic Anhydrase Inhibition.; Chemmedchem, 17:e202200085-e202200085, 2022; PubMed: 35238480; DOI: 10.1002/cmdc.202200085

Experimental method

X-RAY DIFFRACTION (1.223 Å)