7Q3K
Computationally designed thioredoxin subjected to stability optimizing mutations.
Summary for 7Q3K
Entry DOI | 10.2210/pdb7q3k/pdb |
Descriptor | eMM9, SULFATE ION (2 entities in total) |
Functional Keywords | de-novo protein design, deep mutational scanning, stability, screening, de novo protein |
Biological source | synthetic construct |
Total number of polymer chains | 3 |
Total formula weight | 39252.40 |
Authors | Norrild, R.K.,Johansson, K.E.,O'Shea, C.,Lindorff-Larsen, K.,Winther, J.R.,Morth, J.P. (deposition date: 2021-10-27, release date: 2022-11-16, Last modification date: 2024-02-07) |
Primary citation | Norrild, R.K.,Johansson, K.E.,O'Shea, C.,Morth, J.P.,Lindorff-Larsen, K.,Winther, J.R. Increasing protein stability by inferring substitution effects from high-throughput experiments. Cell Rep Methods, 2:100333-100333, 2022 Cited by PubMed: 36452862DOI: 10.1016/j.crmeth.2022.100333 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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