7Q2V

Crystal structure of the C-terminal catalytic domain of Plasmodium falciparum CTP:phosphocholine cytidylyltransferase with 1-methylpyrrolidin-3-ol

Summary for 7Q2V

• Entry DOI: 10.2210/pdb7q2v/pdb
• Descriptor: Cholinephosphate cytidylyltransferase, (3R)-1-methylpyrrolidin-3-ol (3 entities in total)
• Functional Keywords: plasmodium falciparum cct inhibitors fragments, transferase
• Biological source: Plasmodium falciparum
• Total number of polymer chains: 1
• Total formula weight: 20911.27

Authors

Duclovel, C.,Gelin, M.,Krimm, I.,Cerdan, R.,Guichou, J.-F. (deposition date: 2021-10-26, release date: 2022-11-09, Last modification date: 2024-01-31)

• Primary citation: Duclovel, C.,Gelin, M.,Wein, S.,Wengelnik, K.,Krimm, I.,Guichou, J.F.,Cerdan, R.; Crystallographic screening using ultra-low-molecular-weight ligands to guide drug design of PfCCT inhibitors; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.96 Å)