7Q0M
Crystal structure of the peptide transporter YePEPT-K314A in complex with LZNV at 2.66 A
Summary for 7Q0M
| Entry DOI | 10.2210/pdb7q0m/pdb |
| Related | 4W6V 7Q0L |
| Descriptor | Peptide transporter YePEPT, (2~{S})-2-[[(2~{S})-2-azanyl-6-[(4-nitrophenyl)methoxycarbonylamino]hexanoyl]amino]-3-methyl-butanoic acid, UNDECYL-MALTOSIDE (3 entities in total) |
| Functional Keywords | membrane protein, mfs, peptide transporter, solute transporter, inhibitor bound, lznv, pept1 |
| Biological source | Yersinia enterocolitica subsp. palearctica YE-P4 |
| Total number of polymer chains | 1 |
| Total formula weight | 57372.83 |
| Authors | Jeckelmann, J.M.,Stauffer, M.,Ilgue, H.,Fotiadis, D. (deposition date: 2021-10-15, release date: 2022-03-09, Last modification date: 2024-02-07) |
| Primary citation | Stauffer, M.,Jeckelmann, J.M.,Ilgu, H.,Ucurum, Z.,Boggavarapu, R.,Fotiadis, D. Peptide transporter structure reveals binding and action mechanism of a potent PEPT1 and PEPT2 inhibitor. Commun Chem, 5:23-23, 2022 Cited by PubMed: 36697632DOI: 10.1038/s42004-022-00636-0 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.54 Å) |
Structure validation
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