7PY9

Crystal structure of the C-terminal catalytic domain of Plasmodium falciparum CTP:phosphocholine cytidylyltransferase with (pyrrolidin-2-yl)methanol

7PY9 の概要

• エントリーDOI: 10.2210/pdb7py9/pdb
• 分子名称: Cholinephosphate cytidylyltransferase, D-Prolinol (3 entities in total)
• 機能のキーワード: plasmodium falciparum cct inhibitors fragments, transferase
• 由来する生物種: Plasmodium falciparum (malaria parasite P. falciparum)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 21012.42

構造登録者

Duclovel, C.,Gelin, M.,Krimm, I.,Cerdan, R.,Guichou, J.-F. (登録日: 2021-10-09, 公開日: 2022-10-12, 最終更新日: 2024-01-31)

• 主引用文献: Duclovel, C.,Gelin, M.,Wein, S.,Wengelnik, K.,Krimm, I.,Guichou, J.F.,Cerdan, R.; Crystallographic screening using ultra-low-molecular-weight ligands to guide drug design of PfCCT inhibitors; To Be Published,

実験手法

X-RAY DIFFRACTION (2.03 Å)