7PWB

dTDP-sugar epimerase from Coxiella burnetii in complex with dTDP

This is a non-PDB format compatible entry.

Summary for 7PWB

• Entry DOI: 10.2210/pdb7pwb/pdb
• Related: 7PVI
• Descriptor: dTDP-4-dehydrorhamnose 3,5-epimerase, THYMIDINE-5'-DIPHOSPHATE, CITRIC ACID, ... (5 entities in total)
• Functional Keywords: coxiella burnetii, o-antigen, epimerase, enzyme kinetics, sugar binding protein
• Biological source: Coxiella burnetii (strain RSA 493 / Nine Mile phase I)
• Total number of polymer chains: 2
• Total formula weight: 51401.31

Authors

Cross, A.R.,Harmer, N.J.,Isupov, M.N. (deposition date: 2021-10-06, release date: 2022-04-20, Last modification date: 2024-01-31)

• Primary citation: Cross, A.R.,Roy, S.,Vivoli Vega, M.,Rejzek, M.,Nepogodiev, S.A.,Cliff, M.,Salmon, D.,Isupov, M.N.,Field, R.A.,Prior, J.L.,Harmer, N.J.; Spinning sugars in antigen biosynthesis: characterization of the Coxiella burnetii and Streptomyces griseus TDP-sugar epimerases.; J.Biol.Chem., 298:101903-101903, 2022; PubMed: 35398092; DOI: 10.1016/j.jbc.2022.101903

Experimental method

X-RAY DIFFRACTION (1.87 Å)