7PW5
Human SMG1-8-9 kinase complex with AlphaFold predicted SMG8 C-terminus, bound to a SMG1 inhibitor
Summary for 7PW5
Entry DOI | 10.2210/pdb7pw5/pdb |
EMDB information | 13675 |
Descriptor | SMG1,Serine/threonine-protein kinase SMG1,SMG1,Serine/threonine-protein kinase SMG1,SMG1,Serine/threonine-protein kinase SMG1,SMG1,Serine/threonine-protein kinase SMG1, Protein SMG8, Protein SMG9, ... (7 entities in total) |
Functional Keywords | complex, transferase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 566696.19 |
Authors | |
Primary citation | Langer, L.M.,Bonneau, F.,Gat, Y.,Conti, E. Cryo-EM reconstructions of inhibitor-bound SMG1 kinase reveal an autoinhibitory state dependent on SMG8. Elife, 10:-, 2021 Cited by PubMed: 34698635DOI: 10.7554/eLife.72353 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.4 Å) |
Structure validation
Download full validation report