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7PVE

Crystal structure of the C-terminal catalytic domain of Plasmodium falciparum CTP:phosphocholine cytidylyltransferase with 4-bromo-1H-imidazole

Summary for 7PVE
Entry DOI10.2210/pdb7pve/pdb
DescriptorCholinephosphate cytidylyltransferase, 4-bromo-1H-imidazole (3 entities in total)
Functional Keywordsplasmodium falciparum cct inhibitors fragments, transferase
Biological sourcePlasmodium falciparum
Total number of polymer chains1
Total formula weight21104.07
Authors
Duclovel, C.,Gelin, M.,Krimm, I.,Cerdan, R.,Guichou, J.-F. (deposition date: 2021-10-02, release date: 2022-10-05, Last modification date: 2024-01-31)
Primary citationDuclovel, C.,Gelin, M.,Wein, S.,Wengelnik, K.,Krimm, I.,Guichou, J.F.,Cerdan, R.
Crystallographic screening using ultra-low-molecular-weight ligands to guide drug design of PfCCT inhibitors
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.39 Å)
Structure validation

221051

数据于2024-06-12公开中

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