7PUT

Crystal structure of Thioredoxin Reductase from Brugia Malayi in complex with NADP(H)

7PUT の概要

• エントリーDOI: 10.2210/pdb7put/pdb
• 分子名称: Glutaredoxin domain-containing protein, FLAVIN-ADENINE DINUCLEOTIDE, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (6 entities in total)
• 機能のキーワード: glutaredoxin, flavoprotein, selenocysteine, oxidoreductase
• 由来する生物種: Brugia malayi (Filarial nematode worm); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 202015.39

構造登録者

Fata, F.,Ardini, M.,Silvestri, I.,Gabriele, F.,Ippoliti, R.,Gencheva, R.,Cheng, Q.,Arner, E.S.J.,Angelucci, F.,Williams, D.L. (登録日: 2021-09-30, 公開日: 2022-04-06, 最終更新日: 2024-01-31)

• 主引用文献: Fata, F.,Gencheva, R.,Cheng, Q.,Lullo, R.,Ardini, M.,Silvestri, I.,Gabriele, F.,Ippoliti, R.,Bulman, C.A.,Sakanari, J.A.,Williams, D.L.,Arner, E.S.J.,Angelucci, F.; Biochemical and structural characterizations of thioredoxin reductase selenoproteins of the parasitic filarial nematodes Brugia malayi and Onchocerca volvulus.; Redox Biol, 51:102278-102278, 2022; PubMed: 35276442; DOI: 10.1016/j.redox.2022.102278

実験手法

X-RAY DIFFRACTION (2.8 Å)