7PS2

Crystal structure of the receptor binding domain of SARS-CoV-2 beta variant spike glycoprotein in complex with Beta-29 and Beta-53 Fabs

7PS2 の概要

• エントリーDOI: 10.2210/pdb7ps2/pdb
• 関連するPDBエントリー: 7PS1
• 分子名称: Beta-29 Fab light chain, Spike protein S1, Beta-29 Fab heavy chain, ... (9 entities in total)
• 機能のキーワード: sars-cov-2 b.1.1.7 (alpha) variant, b.1.351 (beta) variant, p.1 (gamma) variant, b.1.617.2 (delta) variant, antibody, receptor-binding-domain, spike, neutralisation, viral protein/immune system, viral protein, immune system, viral protein-immune system complex
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 122740.16

構造登録者

Zhou, D.,Ren, J.,Stuart, D.I. (登録日: 2021-09-22, 公開日: 2021-12-15, 最終更新日: 2024-01-31)

• 主引用文献: Liu, C.,Zhou, D.,Nutalai, R.,Duyvesteyn, H.M.E.,Tuekprakhon, A.,Ginn, H.M.,Dejnirattisai, W.,Supasa, P.,Mentzer, A.J.,Wang, B.,Case, J.B.,Zhao, Y.,Skelly, D.T.,Chen, R.E.,Johnson, S.A.,Ritter, T.G.,Mason, C.,Malik, T.,Temperton, N.,Paterson, N.G.,Williams, M.A.,Hall, D.R.,Clare, D.K.,Howe, A.,Goulder, P.J.R.,Fry, E.E.,Diamond, M.S.,Mongkolsapaya, J.,Ren, J.,Stuart, D.I.,Screaton, G.R.; The antibody response to SARS-CoV-2 Beta underscores the antigenic distance to other variants.; Cell Host Microbe, 30:53-, 2022; PubMed: 34921776; DOI: 10.1016/j.chom.2021.11.013

実験手法

X-RAY DIFFRACTION (2.99 Å)