7PKE
C-reactive protein pentamer at pH 7.5 with phosphocholine ligand
Summary for 7PKE
Entry DOI | 10.2210/pdb7pke/pdb |
EMDB information | 13469 |
Descriptor | C-reactive protein, CALCIUM ION, PHOSPHOCHOLINE, ... (4 entities in total) |
Functional Keywords | c-reactive protein, crp, immune system, innate immunity |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 5 |
Total formula weight | 116661.73 |
Authors | Noone, D.P.,Sharp, T.H. (deposition date: 2021-08-25, release date: 2021-12-22, Last modification date: 2022-01-12) |
Primary citation | Noone, D.P.,van der Velden, T.T.,Sharp, T.H. Cryo-Electron Microscopy and Biochemical Analysis Offer Insights Into the Effects of Acidic pH, Such as Occur During Acidosis, on the Complement Binding Properties of C-Reactive Protein. Front Immunol, 12:757633-757633, 2021 Cited by PubMed: 34975846DOI: 10.3389/fimmu.2021.757633 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.3 Å) |
Structure validation
Download full validation report