7PJB

Crystal structure of YTHDC1 with compound PSI_DC1_004

Summary for 7PJB

• Entry DOI: 10.2210/pdb7pjb/pdb
• Descriptor: YTH domain-containing protein 1, (R)-homoproline, SULFATE ION, ... (5 entities in total)
• Functional Keywords: ythdc1, inhibitor, complex, m6a, rna binding protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 43053.23

Authors

Bedi, R.K.,Huang, D.,Caflisch, A. (deposition date: 2021-08-23, release date: 2021-10-20, Last modification date: 2024-01-31)

• Primary citation: Li, Y.,Bedi, R.K.,Nai, F.,von Roten, V.,Dolbois, A.,Zalesak, F.,Nachawati, R.,Huang, D.,Caflisch, A.; Structure-based design of ligands of the m6A-RNA reader YTHDC1; Eur J Med Chem Rep, 5:100057-, 2022; DOI: 10.1016/j.ejmcr.2022.100057

Experimental method

X-RAY DIFFRACTION (1.9 Å)