7PI6
Trypanosoma brucei ISG65 bound to human complement C3d
Summary for 7PI6
Entry DOI | 10.2210/pdb7pi6/pdb |
Descriptor | 65 kDa invariant surface glycoprotein, Complement C3dg fragment, GLYCEROL, ... (5 entities in total) |
Functional Keywords | complement, innate immunity, host-pathogen, sleeping sickness, immune system |
Biological source | Trypanosoma brucei brucei (strain 927/4 GUTat10.1) More |
Total number of polymer chains | 4 |
Total formula weight | 154743.35 |
Authors | Cook, A.D.,Higgins, M.K. (deposition date: 2021-08-19, release date: 2022-07-27, Last modification date: 2024-02-07) |
Primary citation | Macleod, O.J.S.,Cook, A.D.,Webb, H.,Crow, M.,Burns, R.,Redpath, M.,Seisenberger, S.,Trevor, C.E.,Peacock, L.,Schwede, A.,Kimblin, N.,Francisco, A.F.,Pepperl, J.,Rust, S.,Voorheis, P.,Gibson, W.,Taylor, M.C.,Higgins, M.K.,Carrington, M. Invariant surface glycoprotein 65 of Trypanosoma brucei is a complement C3 receptor. Nat Commun, 13:5085-5085, 2022 Cited by PubMed: 36038546DOI: 10.1038/s41467-022-32728-9 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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