7PHX
Tsetse thrombin inhibitor in complex with human alpha-thrombin - acid-stable sulfotyrosine analogue
Summary for 7PHX
| Entry DOI | 10.2210/pdb7phx/pdb |
| Descriptor | Thrombin light chain, Thrombin heavy chain, Tsetse thrombin inhibitor, ... (6 entities in total) |
| Functional Keywords | anticoagulant; exosite ii binding; sulfotyrosine sulfonate analogue, blood clotting |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 3 |
| Total formula weight | 37649.69 |
| Authors | Pereira, P.J.B.,Ripoll-Rozada, J.,Calisto, B.M. (deposition date: 2021-08-18, release date: 2021-10-06, Last modification date: 2024-01-31) |
| Primary citation | Dowman, L.J.,Agten, S.M.,Ripoll-Rozada, J.,Calisto, B.M.,Pereira, P.J.B.,Payne, R.J. Synthesis and evaluation of peptidic thrombin inhibitors bearing acid-stable sulfotyrosine analogues. Chem.Commun.(Camb.), 57:10923-10926, 2021 Cited by PubMed: 34596182DOI: 10.1039/d1cc04742f PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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