7PFM

A SARS-CoV2 major protease non-covalent ligand structure determined to 2.0 A resolution

Summary for 7PFM

• Entry DOI: 10.2210/pdb7pfm/pdb
• Descriptor: Replicase polyprotein 1ab, N-[(1R)-2-(tert-butylamino)-2-oxidanylidene-1-pyridin-3-yl-ethyl]-N-(4-tert-butylphenyl)-1H-imidazole-5-carboxamide (3 entities in total)
• Functional Keywords: cysteine protease, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2)
• Total number of polymer chains: 2
• Total formula weight: 68518.19

Authors

Moche, M.,Moodie, L.,Strandback, E.,Nyman, T.,Sandstrom, A.,Akaberi, D.,Lennerstrand, J. (deposition date: 2021-08-11, release date: 2022-08-24, Last modification date: 2024-01-31)

• Primary citation: Moche, M.,Moodie, L.,Strandback, E.,Nyman, T.,Akaberi, D.,Lennerstrand, J.; The SARS-CoV2 major protease (Mpro) in complex with a non-covalent inhibitory ligand at 2 A resolution; To Be Published,

Experimental method

X-RAY DIFFRACTION (2 Å)