7PFM

A SARS-CoV2 major protease non-covalent ligand structure determined to 2.0 A resolution

7PFM の概要

• エントリーDOI: 10.2210/pdb7pfm/pdb
• 分子名称: Replicase polyprotein 1ab, N-[(1R)-2-(tert-butylamino)-2-oxidanylidene-1-pyridin-3-yl-ethyl]-N-(4-tert-butylphenyl)-1H-imidazole-5-carboxamide (3 entities in total)
• 機能のキーワード: cysteine protease, viral protein
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 68518.19

構造登録者

Moche, M.,Moodie, L.,Strandback, E.,Nyman, T.,Sandstrom, A.,Akaberi, D.,Lennerstrand, J. (登録日: 2021-08-11, 公開日: 2022-08-24, 最終更新日: 2024-01-31)

• 主引用文献: Moche, M.,Moodie, L.,Strandback, E.,Nyman, T.,Akaberi, D.,Lennerstrand, J.; The SARS-CoV2 major protease (Mpro) in complex with a non-covalent inhibitory ligand at 2 A resolution; To Be Published,

実験手法

X-RAY DIFFRACTION (2 Å)