7PCF

Human methemoglobin bound to Staphylococcus aureus hemophore IsdB

Summary for 7PCF

Entry DOI	10.2210/pdb7pcf/pdb
EMDB information	13319
Descriptor	Hemoglobin subunit alpha, Hemoglobin subunit beta, Iron-regulated surface determinant protein B, ... (4 entities in total)
Functional Keywords	iron acquisition, hemophore, hemoglobin, neat domain, metal transport
Biological source	Staphylococcus aureus subsp. aureus MW2 More
Total number of polymer chains	4
Total formula weight	119059.78
Authors	De Bei, O.,Gianquinto, E.,Chirgadze, D.Y.,Hardwick, S.W.,Spyrakis, F.,Luisi, B.F.,Campanini, B. (deposition date: 2021-08-03, release date: 2022-04-13, Last modification date: 2024-07-17)
Primary citation	De Bei, O.,Marchetti, M.,Ronda, L.,Gianquinto, E.,Lazzarato, L.,Chirgadze, D.Y.,Hardwick, S.W.,Cooper, L.R.,Spyrakis, F.,Luisi, B.F.,Campanini, B.,Bettati, S. Cryo-EM structures of staphylococcal IsdB bound to human hemoglobin reveal the process of heme extraction. Proc.Natl.Acad.Sci.USA, 119:e2116708119-e2116708119, 2022 Cited by PubMed: 35357971 DOI: 10.1073/pnas.2116708119 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (5.82 Å)

Structure validation