7PC2

HIV-1 Env (BG505 SOSIP.664) in complex with the IgA bNAb 7-269 and the antibody 3BNC117.

7PC2 の概要

• エントリーDOI: 10.2210/pdb7pc2/pdb
• EMDBエントリー: 13316
• 分子名称: 7-269 IgA Fab heavy chain, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (15 entities in total)
• 機能のキーワード: hiv, antibody, bnab, env, viral protein
• 由来する生物種: Homo sapiens; 詳細
• タンパク質・核酸の鎖数: 18
• 化学式量合計: 546142.23

構造登録者

Fernandez, I.,Bontems, F.,Pehau-Arnaudet, G.,Rey, F. (登録日: 2021-08-03, 公開日: 2022-02-23, 最終更新日: 2022-03-16)

• 主引用文献: Lorin, V.,Fernandez, I.,Masse-Ranson, G.,Bouvin-Pley, M.,Molinos-Albert, L.M.,Planchais, C.,Hieu, T.,Pehau-Arnaudet, G.,Hrebik, D.,Girelli-Zubani, G.,Fiquet, O.,Guivel-Benhassine, F.,Sanders, R.W.,Walker, B.D.,Schwartz, O.,Scheid, J.F.,Dimitrov, J.D.,Plevka, P.,Braibant, M.,Seaman, M.S.,Bontems, F.,Di Santo, J.P.,Rey, F.A.,Mouquet, H.; Epitope convergence of broadly HIV-1 neutralizing IgA and IgG antibody lineages in a viremic controller.; J.Exp.Med., 219:-, 2022; PubMed: 35230385; DOI: 10.1084/jem.20212045

実験手法

ELECTRON MICROSCOPY (2.8 Å)