7PA5
Complex between the beta-lactamase CMY-2 with an inhibitory nanobody
Summary for 7PA5
Entry DOI | 10.2210/pdb7pa5/pdb |
Descriptor | Beta-lactamase, nanobody, GLYCEROL, ... (5 entities in total) |
Functional Keywords | single domain camelid antibody cephalosporinase, hydrolase |
Biological source | Escherichia coli More |
Total number of polymer chains | 2 |
Total formula weight | 54291.15 |
Authors | Frederic Cawez, F.C.,Frederic Kerff, F.K.,Moreno Galleni, M.G.,Raphael Herman, R.H. (deposition date: 2021-07-29, release date: 2022-11-16, Last modification date: 2024-01-31) |
Primary citation | Cawez, F.,Mercuri, P.S.,Morales-Yanez, F.J.,Maalouf, R.,Vandevenne, M.,Kerff, F.,Guerin, V.,Mainil, J.,Thiry, D.,Saulmont, M.,Vanderplasschen, A.,Lafaye, P.,Ayme, G.,Bogaerts, P.,Dumoulin, M.,Galleni, M. Development of Nanobodies as Theranostic Agents against CMY-2-Like Class C beta-Lactamases. Antimicrob.Agents Chemother., 67:e0149922-e0149922, 2023 Cited by PubMed: 36892280DOI: 10.1128/aac.01499-22 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.184 Å) |
Structure validation
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