7P6L

Heme domain of CYP505A30, a fungal hydroxylase from Myceliophthora thermophila, bound to dodecanoic acid

7P6L の概要

• エントリーDOI: 10.2210/pdb7p6l/pdb
• 分子名称: Bifunctional cytochrome P450/NADPH--P450 reductase, PROTOPORPHYRIN IX CONTAINING FE, LAURIC ACID, ... (4 entities in total)
• 機能のキーワード: cytochrome p450 monooxygenase hydroxylase, oxidoreductase
• 由来する生物種: Myceliophthora thermophila (strain ATCC 42464 / BCRC 31852 / DSM 1799) (Sporotrichum thermophile)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 213596.41

構造登録者

Opperman, D.J.,Aschenbrenner, J.C.,Tolmie, C.,Ebrecht, A.C. (登録日: 2021-07-16, 公開日: 2022-02-09, 最終更新日: 2024-01-31)

• 主引用文献: Aschenbrenner, J.C.,Ebrecht, A.C.,Tolmie, C.,Smit, M.S.,Opperman, D.J.; Structure of the fungal hydroxylase, CYP505A30, and rational transfer of mutation data from CYP102A1 to alter regioselectivity; Catalysis Science And Technology, 11:7359-7367, 2021; DOI: 10.1039/D1CY01348C

実験手法

X-RAY DIFFRACTION (2.33 Å)